Snap-8 (10mg)

What is SNAP-8 (10mg)?

SNAP-8 (10mg), also known as Acetyl Octapeptide-3, is a synthetic peptide composed of eight amino acids, designed for laboratory investigations involving cellular signaling and peptide–protein interactions. It is structurally related to fragments of proteins involved in neurotransmitter release and cellular communication, and is commonly studied in biochemical and dermatological research models. Identification:

• Chemical Formula: C₄₁H₇₀N₁₆O₁₆S
• Molecular Weight: 1075.16 g/mol
• CAS Number: 868844-74-0
• Sequence: Acetyl-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH₂

Research-grade SNAP-8 is typically produced with high purity and verified using analytical techniques such as high-performance liquid chromatography (HPLC) and mass spectrometry (MS). In laboratory settings, SNAP-8 has been studied for its interactions with cellular signaling proteins involved in vesicle fusion and neurotransmitter release.

What are the key features of SNAP-8 (10mg)?

• Synthetic octapeptide composed of eight amino acids
• Purity typically ≥95%, verified through analytical testing
• Supplied as 10 mg lyophilized peptide in a sealed research vial
• Studied in cellular signaling and peptide–protein interaction research
• For laboratory research use only

How is SNAP-8 (10mg) synthesized?

SNAP-8 (10mg) is produced using solid-phase peptide synthesis (SPPS), a widely used method for constructing peptides with precise amino acid sequences. During SPPS, protected amino acids are sequentially added to a solid support until the complete octapeptide structure is formed. After synthesis, the peptide is purified by high-performance liquid chromatography (HPLC) to achieve high purity. Molecular identity and structural integrity are verified through mass spectrometry (MS) and other analytical techniques. The final peptide is lyophilized, improving stability and enabling long-term storage for laboratory use.

What is SNAP-8 (10mg) being studied for? What are its possible benefits?

In laboratory research, SNAP-8 (10mg) has been studied in models investigating cellular communication processes related to neurotransmitter release and vesicle transport. The peptide is structurally related to regions of proteins involved in the SNARE complex, which plays a role in cellular signaling mechanisms. Research areas involving SNAP-8 include:

• Cellular signaling pathway studies
• Protein–peptide interaction research
• Neurotransmitter release and vesicle transport models
• Dermatological and cosmetic science investigations
• Cell communication and protein regulation studies

Experimental findings suggest that peptides derived from SNARE-related protein fragments may influence signaling events involved in vesicle fusion and cellular communication. These potential biological effects remain under investigation in laboratory environments.

How does SNAP-8 (10mg) work in research studies?

In experimental models, SNAP-8 (10mg) is studied for its potential interaction with proteins associated with vesicle fusion and neurotransmitter release. The peptide sequence resembles a fragment of the SNAP-25 protein, a component of the SNARE complex involved in cellular communication processes. Researchers investigate how the peptide may influence protein interactions involved in signal transmission and membrane fusion events. By studying these mechanisms, scientists aim to better understand how peptide fragments may affect cellular communication pathways. These mechanisms remain the subject of ongoing research and are examined primarily in biochemical and cell culture models.

What dosing information exists for SNAP-8 (10mg)?

Research involving SNAP-8 (10mg) has largely been conducted in in vitro experimental systems. Laboratory experiments often investigate the peptide at nanomolar to micromolar concentrations to study protein interactions and cellular responses. In some experimental models, concentrations ranging from 10 µM to 100 µM have been examined depending on the study design and biological system being evaluated. Because SNAP-8 is used as a research compound, no standardized human dosing guidelines exist, and its use is restricted to controlled laboratory environments.

How should SNAP-8 (10mg) be stored and handled?

• Store under temperature-controlled conditions per laboratory protocol and certificate of analysis.
• For extended storage, follow temperature conditions specified in the product certificate of analysis.
• Protect the lyophilized peptide from light, heat, and moisture.
• Room-temperature exposure during transport is acceptable for short periods.
• Once reconstituted, store under appropriate temperature-controlled conditions per laboratory protocol for short-term use.
• Avoid repeated freeze-thaw cycles to preserve peptide integrity.
• Refer to the batch certificate of analysis for batch-specific stability data.

Where can I read more research about SNAP-8 (10mg)?

Researchers interested in SNAP-8 and related peptide signaling research may consult the following scientific publications:

1. afoya LCR, Mameli M, Miyashita T, Guzowski JF, Valenzuela CF, Wilson MC. Expression and function of SNAP-25 as a universal SNARE component in GABAergic neurons. Journal of Neuroscience. 2006;26(30):7826-7838. doi:10.1523/jneurosci.1866-06.2006
2. Khvotchev M, Soloviev M. SNARE modulators and SNARE mimetic peptides. Biomolecules. 2022;12(12):1779. doi:10.3390/biom12121779
3. Blanes‐Mira C, Clemente J, Jodas G, et al. A synthetic hexapeptide (Argireline) with antiwrinkle activity. International Journal of Cosmetic Science. 2002;24(5):303-310. doi:10.1046/j.1467-2494.2002.00153.x

Compliance Statement

This product is intended for laboratory research use only and is not approved for human or veterinary use.