Hexarelin (5mg)

What is Hexarelin (5mg)?

Hexarelin (5mg) is a synthetic hexapeptide composed of six amino acids. Also known as Examorelin, it belongs to a class of growth hormone–releasing peptides (GHRPs) that are being researched in studies on endocrine signaling.

Identification

• Chemical Formula: C₄₇H₅₈N₁₂O₆
• Molecular Weight: 887.059 g/mol
• CAS Number: 140703-51-1

This peptide has been studied in laboratory models focused on growth hormone regulation and metabolic signaling. Research-grade material is typically produced at high purity levels (≥95%, verified by analytical testing). Investigations remain experimental and are limited to controlled research environments.

What are the key features of Hexarelin (5mg)?

• High research-grade purity (≥95% typical analytical standard)
• Supplied as a 5 mg lyophilized peptide in a sealed vial
• Hexapeptide structure consisting of six amino acids
• Studied in growth hormone signaling research models
• Shelf life of approximately 24 months under recommended storage conditions
• For laboratory research use only

How is Hexarelin (5mg) synthesized?

Hexarelin (5mg) is produced using solid-phase peptide synthesis (SPPS), a standard laboratory method that allows for precise control over the peptide's sequence. The six-amino-acid structure is synthesized step-by-step using protected amino acid intermediates. After synthesis, the peptide is purified using high-performance liquid chromatography (HPLC) to achieve high purity. Mass spectrometry (MS) is used to confirm the peptide’s molecular weight and structure. The final product is lyophilized to improve stability and storage for research applications.

What is Hexarelin (5mg) being studied for? What are its possible benefits?

Hexarelin (5mg) has been studied in laboratory research focused on endocrine signaling and metabolic regulation. Investigations have explored its potential role in:

• Growth hormone secretion
• Cardiovascular physiology
• Metabolic regulation
• Muscle biology

In experimental settings, Hexarelin has been studied for its influence on hormonal signaling pathways and cellular responses related to growth and metabolism. These possible biological effects are under investigation and based on controlled laboratory observations, not clinical outcomes.

How does Hexarelin (5mg) work in research studies?

In laboratory models, Hexarelin (5mg) is being studied for its interaction with signaling pathways that regulate growth hormone release. As a growth hormone–releasing peptide, it is being explored for its potential to stimulate hormone secretion in experimental endocrine systems. Hexarelin may modulate cellular signaling pathways involved in growth hormone production and metabolic regulation in research settings. Studies have also examined its effects on cardiovascular tissues and metabolic responses. These mechanisms remain investigational and do not indicate clinical use.

What dosing information exists for Hexarelin (5mg)?

Preclinical studies involving Hexarelin have primarily been conducted in animal models and cell culture systems. In animal research, the peptide has been studied at microgram-per-kilogram (µg/kg) dosing ranges, depending on the experimental objectives. In vitro experiments often evaluate nanomolar to micromolar concentrations to observe cellular responses. Dosing protocols and exposure durations vary across studies. There are no established human dosing guidelines for Hexarelin (5mg), as it is intended solely for laboratory research use.

How should Hexarelin (5mg) be stored and handled?

Hexarelin (5mg) should be stored at 2–8 °C for routine laboratory handling. For long-term storage, temperatures of ≤–20 °C are recommended to preserve peptide stability. Protect the vial from light and excessive moisture. Once reconstituted using sterile laboratory-grade solvent, the solution should generally be stored at 2–8 °C for short-term use. Avoid repeated freeze–thaw cycles, as these may affect structural stability. The product typically remains stable for approximately 24 months when stored under recommended conditions. Standard laboratory protective equipment should be used during handling, and disposal should follow institutional biosafety procedures.

Where can I read more research about Hexarelin (5mg)?

1. National Center for Biotechnology Information. PubChem Compound Summary for CID 6918297, Examorelin. https://pubchem.ncbi.nlm.nih.gov/compound/Examorelin
2. Massoud AF, Hindmarsh PC, Matthews DR, Brook CG. The effect of repeated administration of hexarelin, a growth hormone releasing peptide, and growth hormone releasing hormone on growth hormone responsivity. Clin Endocrinol (Oxf). 1996;44(5):555-562. doi:10.1046/j.1365-2265.1996.722543.x
3. Micic D, Popovic V, Kendereski A, Peino R, Dieguez C, Casanueva FF. The sequential administration of growth hormone‐releasing hormone followed 120 minutes later by hexarelin, as an effective test to assess the pituitary GH reserve in man. Clinical Endocrinology. 1996;45(5):543-551. doi:10.1046/j.1365-2265.1996.00841.x
4. Arvat E, Di Vito L, Ramunni J, et al. Low hexarelin dose and pyridostigmine have additive effect and potentiate to the same extent the GHRH-induced GH response in man. Clin Endocrinol (Oxf). 1997;47(4):495-500. doi:10.1046/j.1365-2265.1997.3081114.x
5. Muccioli G, Broglio F, Valetto MR, et al. Growth hormone-releasing peptides and the cardiovascular system. Ann Endocrinol (Paris). 2000;61(1):27-31.

Compliance Statement

This product is intended for laboratory research use only and is not approved for human or veterinary use.